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2021 Mercedes-Benz E 350

13 owner complaints — the most of any E 350 model years, 2.2× the typical year. 12 recalls, 25 service bulletins.

13complaints · 0 crashes, 1 fires
12recalls
25manufacturer bulletins
38,601 mimedian mileage at failure

Problems owners report

Complaints filed with NHTSA about the 2021 Mercedes-Benz E 350, by the system named in each complaint. One complaint can name several.

  • Electrical system4
  • Engine4
  • Power train3
  • Back over prevention3
  • Fuel/propulsion system2
  • Service brakes1
  • Fuel system, gasoline1

NHTSA ODI complaints (public domain) · updated 23 Oct 2026 · 0 injuries and 0 deaths reported

Compared with other years

’20’21’22’24’2613’20’21’23’2613

NHTSA ODI complaints by model year

Recalls

23V445000 · Fuel system, gasoline26 Jun 2023 · 143,551 vehicles

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2023 C-Class, E-Class, S-Class, CLS, SL, GT, GLC, GLE, GLS, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle details. The fuel pump may shutdown, which can result in a loss of drive power.

22V365000 · Communication20 May 2022 · 242,722 vehicles

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2017-2022 CLA-Class, GLA-Class, GLE-Class, GLS-Class, SLC-Class, A-Class, AMG GT-Class, C-Class, E-Class, S-Class, SL-Class, GLC-Class, CLS-Class, GLB-Class, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle model details. An error in the communication module's SIM card software can cause a mobile network connection failure, disabling the emergency call (eCall) system.

22V232000 · Back over prevention8 Apr 2022 · 126,443 vehicles

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2018-2021 CLA-Class, GLE/GLS-Class, A-Class, C-Class, E-Class, E-Class Coupe/Convertible, GLA/GLB-Class, GLC-Class, and CLS-Class vehicles. Please refer to MBUSA's recall report for specific vehicle model details. The rearview camera may not display the rearview image due to a software error. As such, these vehicles fail to comply with the requirements of Federal Motor Vehicle Safety Standard number 111, "Rear Visibility."

22V189000 · Steering25 Mar 2022 · 8,396 vehicles

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2022 C-Class, E-Class, S-Class, SL, EClass Coupe/Convertible, CLS, AMG GT 4-doors Coupe, and EQS vehicles with a heated leather steering wheel. Due to a software error in the hand detection control unit, the hands-off detection might not detect when the driver's hands are away from the steering wheel when using the Active Distance Assist DISTRONIC system.

21V527000 · Air bags12 Jul 2021 · 542 vehicles

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 CLS450, AMG E53, AMG CLS53, E350, E450, AMG GT43, AMG GT53, 2020 S450, S560, G550, AMG GLC63, 2020-2021 GLC300, and AMG G63 vehicles. The side crash sensor connectors may come loose, which could delay the activation of air bags and seatbelts during a side impact crash.

21V483000 · Seat belts25 Jun 2021 · 4,917 vehicles

Mercedes-Benz, LLC (MBUSA) is recalling certain 2021 G550, AMG G63, E350, E450, AMG CLS53, AMG E53, AMG GT43, AMG GT53, AMG GT63, 2021-2022 CLS450, and AMG E63 vehicles. The rear seat belt automatic locking retractors may deactivate early, which can prevent the child restraint system from securing properly. As such, these vehicles fail to comply with the requirements of Federal Motor Vehicle Safety Standard number 208, "Occupant Crash Protection."

21V354000 · Back over prevention14 May 2021 · 343,191 vehicles

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2019-2021 CLA-Class, GLE/GLS-Class, A-Class, E-Class, E-Class Coupe and Convertible, GLA/GLB-Class, GLC-Class, CLS-Class, and AMG GT-Class 4-door Coupe vehicles. Please refer to MBUSA's recall report for specific vehicle model details. The MBUX multimedia system software may cause the display to remain black, or reboot after startup. This could result in the rearview camera image not displaying properly. As such, these vehicles fail to comply with the requirements of Federal Motor Vehicle Safety Standard (FMVSS) number 111, "Rear Visibility."

21V230000 · Seats1 Apr 2021 · 8,634 vehicles

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 C-Class, E-Class, E-Class Coupe and Convertible, GLC, CLS, AMG GT 4-door Coupe and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle model details. A faulty electrical contact within the seat position switch may prevent the driver and passenger air bags and seat belt force limiters from properly activating during a crash.

21V228000 · Back over prevention1 Apr 2021 · 6 vehicles

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 E350, E450, E450 Wagon, and AMG E63 vehicles. The parking control unit may fail to display the rearview camera image and cause the parking sensors to misidentify or fail to detect objects.

21V216000 · Seats26 Mar 2021 · 109 vehicles

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 E350, E450, E450 Wagon, E63S AMG, 2020 E63S AMG Wagon, and 2020-2021 E53 AMG vehicles. The passenger seat limiter may allow the seat to be positioned too close to the air bag.

21V058000 · Electrical system5 Feb 2021 · 1,292,258 vehicles

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2016 - 2021 CLA-Class, GLA-Class, GLE-Class, GLS-Class, SLC-Class, A-Class, GT-Class, C-Class, E-Class, S-Class, CLS-Class, SL-Class, B-Class, GLB-Class, GLC-Class, and G-Class vehicles. Please refer to the Part 573 report for specific vehicle model details. The software design of the communication module may fail to communicate the correct vehicle location for the emergency call system (eCall) in the event of a crash.

20V673000 · Seats30 Oct 2020 · 1,337 vehicles

Mercedes-Benz USA, LLC. (MBUSA) is recalling certain 2021 E350 and E450, 2019-2021 AMG E53 and 2020-2021 AMG E63 vehicles. The front passenger seat may be missing the mechanical seat adjustment range limit stop, allowing the seat to move outside of the acceptable range in relation to the air bag.

Whether a recall was fixed on a particular car is known only to the manufacturer: check the VIN at nhtsa.gov/recalls.

NHTSA recalls · summaries in NHTSA's own words

Service bulletins

What Mercedes-Benz told its dealers about the 2021 Mercedes-Benz E 350: known faults, fixes and updates.

BulletinSummary
11010818Complaint Transmission control unit Y3/8n4 (fully integrated transmission control unit (VGS)) not listed in quick test and/or no communication possible with VGS. Cause Transmission control unit Y3/8n4 Remedy It is important that LI54.15-P-057373 is processed before replacing any component parts (transmission 722.9). After processing and complying with the above documents, perform a reset on the transmission control unit Y3/8n4 (VGS) (ignition reset), check that the transmission connector is seated correctly and inspect the PINs for concerns. If communication with the VGS cannot be established
11010755Complaint After a control unit replacement of "N112/9 - control unit for telematics services (HERMES)" or the "N112/2 - control unit for telematics services (RAMSES)", the Digital Extras (previously Mercedes me) cannot be activated. The DTC B15CE00 is active or active+saved. In vehicles with "N112/9 - control unit for telematics services (HERMES)": The message "SOS - service not activated" permanently lights up in the instrument cluster AND the actual value "Error when replacing certificate (CEP.36)" is displayed in the actual values for the activation status under "Registration status" (see
11010494Complaint Rear lamps fogged up/not leaktight. Cause Fogging of the rear lamps is a natural phenomenon, which can occur under certain climatic conditions. This does not lead to any technical impairment of the rear lamps. Remedy Rear lamp: Remedy 1: Clearing fogged/condensed rear lamps: 1. Drive the vehicle into the workshop (temperature higher than +18 C/+64.4 F) Note: Do not wash the vehicle or subject it to high-pressure cleaning before the defogging test. 2. Switch off the engine and connect battery support via a charger. 3. Open the trunk. 4. Switch on the exterior lighting. 5. Leave the ve
11010455Complaint Only vehicles with a variable transfer case are affected. Can be identified through control unit N45 or N15/7 in the quick test When accelerating with light load, vibrations or jolting sensation may come from the drivetrain Cause Modified oil quality of the transfer case over time Remedy Check initial quick test for faults in the following control units N45 - All-wheel drive (ARS) N127 - 'Drivetrain' (PTCU) control unit Y3/8 - Transmission control for 9-gear transmission (VGS) N3/10 - Engine electronics for combustion engine If faults are present, process them as per the guided test
11009122Complaint Washer fluid system leaks Cause Various possible causes: 1. Washer fluid reservoir itself. 2. Seal on washer fluid pump/washer fluid reservoir. 3. Washer fluid pump. 3.1. Distributor housing leaks. 3.2. Pump fitting leaks. 3.3. Washer fluid hose cannot be snapped into place on pump fitting. 3.4. Washer fluid hose will not stay on pump fitting, although connector OK. 4. Washer fluid line. 4.1 Connector will not stay on pump fitting because it is broken. 4.2 Sealing ring in connector missing. 4.3 Sealing ring in connector fitted, but deformed and therefore leaks. 4.4 Damage to washer l
11009025Mercedes-Benz AG ("MBAG"), the manufacturer of Mercedes-Benz vehicles, has determined that on certain Model Year (MY) 2018 - 2024 E-Class, S-Class & AMG GT (213, 217, 222, 223 and 290 platforms) vehicles, the low pressure fuel line does not meet current production specifications. Therefore, it is possible that accelerated aging in the area of connection could occur, resulting in a leak. A risk of fire can be ruled out. MBUSA will conduct an Emission Service Campaign. An authorized Mercedes-Benz dealer will replace the braided hose of low-pressure fuel line and install a heat shield over the n
11008880Complaint After a control unit replacement of "N112/9 - control unit for telematics services (HERMES)" or the "N112/2 - control unit for telematics services (RAMSES)", the Digital Extras (previously Mercedes me) cannot be activated. The DTC B15CE00 is active or active+saved. In vehicles with "N112/9 - control unit for telematics services (HERMES)": The message "SOS - service not activated" permanently lights up in the instrument cluster AND the actual value "Error when replacing certificate (CEP.36)" is displayed in the actual values for the activation status under "Registration status" (see
11008873Complaint Tension-releasing impact of the propeller shaft with the force-free in D "KID" function, after vehicle has stopped. Cause The tension-releasing jolt in the drivetrain originates as a result of the "release" of energy stored when braking through the force-free switch after stopping. It is suspected that the longitudinal bearing is being placed under tension here as a result of the vehicle "dropping off". Remedy 1. Mark the installation position of the joint prior to the removal (picture a+b). This is important for vehicles with a weighted drivetrain ex factory to ensure correct instal
11008712Complaint Check engine light on. One of the below fault codes is current in the engine control module (N3/10). P04DB29, P04DB31, P04DB79 Cause Open circuit or high resistance to crankcase vent line contact Remedy 1. Check the electrical connector for the relevant vent line contact switch noted below. Refer to attached photos of connection locations. 2. Ensure the bolted connection is secure and bolt can be torqued (9Nm). 3. Check continuity from vent line connection to ME control unit. Repair wire if damage is found. The circuit from ME provides 5V and is pulled to 0V when the ground connecti
11008323Complaint Headlamps fogged or droplets forming. Cause Due to its outlet openings, the headlamp is an "open system". This means that acidic gases, moisture, dirt and exhaust gases can penetrate into the headlamp. This can lead to the formation of condensation on the lens of the headlamp. The headlamps comply with all applicable US standards and regulations. Remedy Check housing cover of lamp unit for natural fogging or condensation as per LI82.10-P-078301. If a reduction in the degree of fogging is visible, the desiccant packs can be used once the condensation has completely evaporated. Note: O
11008091Complaint During a phone call, the called party has difficulty understanding/cannot understand the driver, or interference/background noises are audible to the called party during a call. It becomes increasingly difficult to understand as the speed rises. Cause A. Seating of the microphones in the headliner. Side edges are covered by the textile cover (see picture "1") B. Assembly of microphones (B25/20 or B25/21) in the headliner. C. Dirt inside the microphone housing Remedy 1. Press finger on rear of microphone (on adhesive tape) 2. Remove microphone cap from the front 3. Eliminate protrudin
11008056Complaint Check engine light on. Fault code P207273 - "Throttle actuator valve is blocked due to ice" stored. Engine may crank and not start. Fault code P210185 may also be stored. Cause Moisture freezing on throttle actuator during extreme low ambient temperatures. Remedy Update software of engine control module. Software increases throttle valve flapping after engine turned off to prevent moisture buildup.
11007974Complaint Headlamps leaking or fogged Cause The fogging of the headlamp is a natural phenomenon which can occur under certain climatic conditions. In contrast to a leaky headlamp, physical fogging does not result in a technical impairment of the headlamp. A leak test must be performed to determine if physical fogging exists or if the headlamp is leaky. Remedy In advance, observe LI82.10-P-078301 "Headlamps or Front Fog Lamps Leaking or Fogged". 1. Prepare headlamp/check for external damage: For headlamps with a closed system 1. Check the headlamps for any external damage and check also for cor
11007956Mercedes-Benz AG, the manufacturer of Mercedes-Benz vehicles, has determined that on certain MY 2020-2023 CLS (257 platform), E-Class (213 and 238 platform), GLE (167 platform), and AMG GT 4-Door (290 platform) vehicles, the engine control unit software does not correspond to current production specifications. As a consequence, the functionality of the post-catalyst oxygen sensor may be impaired due to increased thermal loading. MBUSA will conduct a service campaign. An authorized Mercedes-Benz dealer will update the engine control unit software.
11007753Complaint Headlamp or front fog lamp leaky or fogged Cause Fogging of the headlamps is a natural phenomenon, which can occur under certain climatic conditions. It does not lead to any technical impairment of the headlamp. Headlamps comply with all applicable standards. If a pressure compensation diaphragm is fitted in the housing cover, then the lamp unit is a "closed system". Remedy Headlamp: Remedy 1 Clearing fogged/condensed LED headlamps and LED rear lamps: 1. Drive vehicle into workshop (temperature higher than +18 C/+64.4 F) and connect the exhaust extraction. Note: Do not perform an eng
11007728Complaint To insure vehicle down time is kept at a minimum and all required information is available when case is escalated, as well as assist technicians with checks that may help lead in resolving issue without case creation. THIS LI IS NOT TO BE USED AS A REASON FOR CASE CREATION BUT AS A GUIDE IF A CASE IS NEEDED Cause There are, at times, additional steps workshops can do to help diagnose and rectify transmission complaints. Remedy When opening a case for transmissions a EEPROM, Quick Test, and VGS CUL are absolutely necessary Please also check for any relevant LIs before opening case. Al
11005344Complaint Customer complaints relating to automatic transmission 725.0 (NAG3 Classic / 9G-TRONIC automatic transmission) and 725.1 (NAG3 facelift/9G-TRONIC automatic transmission facelift) For faster, more effective and more targeted diagnosis, Intelligent Predictive Repair (IPR) has been developed and integrated into XENTRY Diagnosis. This ensures an automated diagnosis process. Cause As part of the on-going quality monitoring process and associated quality and damaged part appraisals, a high number of ineffective repairs have been discovered. Such ineffective repairs have a negative impact o
11005331Complaint Only vehicles with a variable transfer case are affected. Can be identified through control unit N45 or N15/7 in the quick test When accelerating with light load, vibrations or jolting sensation may come from the drivetrain Cause Modified oil quality of the transfer case over time Remedy Check initial quick test for faults in the following control units N45 - All-wheel drive (ARS) N127 - 'Drivetrain' (PTCU) control unit Y3/8 - Transmission control for 9-gear transmission (VGS) N3/10 - Engine electronics for combustion engine If faults are present, process them as per the guided test
11005314Complaint Yellow Coolant warning comes on in cluster Fault codes below are current or stored in MED41 P0A0500- The actuation of the circulation pump for the low-temperature circuit has an open circuit. P00B700- The coolant flow is too low. P0C7300- Circulation pump 1 for the low-temperature circuit has a malfunction. Cause Air may be trapped in the coolant circuit for transmission cooler Remedy Check coolant level. -If coolant level is low, locate source of leak and correct. -If coolant level is ok, perform procedure in attached instructions to bleed the coolant circuit to transmission cooler.
11005313Complaint Check engine light on and fault code P019185 current or stored in MED41 control unit. Adaptation and misfire faults may also be stored. Vehicle may enter limp home mode. Cause False detection of rail pressure sensor out of range. Remedy Update software of engine control module N3/10. Reset mixture adaptation and clear fault codes.
11005294Complaint Rear lamps fogged up/not leaktight. Cause Fogging of the rear lamps is a natural phenomenon, which can occur under certain climatic conditions. This does not lead to any technical impairment of the rear lamps. Remedy Rear lamp: Remedy 1: Clearing fogged/condensed rear lamps: 1. Drive the vehicle into the workshop (temperature higher than +18 C/+64.4 F) Note: Do not wash the vehicle or subject it to high-pressure cleaning before the defogging test. 2. Switch off the engine and connect battery support via a charger. 3. Open the trunk. 4. Switch on the exterior lighting. 5. Leave the ve
11003212Complaint Noticeable vibrations at the steering wheel: At speeds between 40mph and 75mph On straight stretches of road and in long corners With driver assistance systems switched on Cause Control oscillations in the electric power steering. Remedy Perform software update of electric power steering (N68). Note: Please ensure newest Xentry release software is installed and all addons are updated. After the software update, teach in the steering limitations of the electric power steering again: 1. Start engine 2. Turn steering wheel all the way to the left and briefly hold at the steering limi
11003205Complaint The driver's seat memory settings do not synchronize with the driver's user profile as described in the operator's manual. Driver's seat settings are not transferred to the vehicle. Cause The driver's seat does not support the profile synchronization feature on these vehicles. Remedy There is no remedy for this complaint. The vehicle is working as designed. Note: Do not replace any parts.
10253703This is to notify you of the Service Campaign OTA update for the MBUX system software in 750,313 Model Year (MY) MY19-24 A-Class, CLA, CLS, E-Class, EQB, GLA, GLB, GLC, GLE, GLS, GT 4-door (177, 118, 257, 213, 238, 243, 247, 253,167, 290 platform) vehicles. The vehicles will not be visible or flagged in VMI or EVA. Mercedes-Benz AG, the manufacturer of Mercedes-Benz vehicles, has determined that on certain MY19-24 A-Class, C-Class, CLA, CLS, E-Class, EQB, GLA, GLC, GLE, GLS, GT 4-door (177, 118, 257, 213, 238, 243, 247, 253, 167, 290 platform) vehicles, the MBUX system software does not cor
10252777Tailgate opens unintentionally. Accidental or unnoticed activation of the button to open the tailgate on the vehicle key. E.g. when stored in trouser pocket, handbag etc. Remedy As of the 6th generation, the vehicle key can be recoded so that the tailgate no longer opens as a result of a long press on the button, but by double-clicking on the button instead. The recoding can be carried out as follows: 1. Add AO code O19 in VeDoc (O as in the letter "O" for Oscar, not the number "0"/zero) 2. EZS N73: Perform SCN coding 3. Deactivate the vehicle key (a successful deactivation is indic

NHTSA manufacturer communications (public domain)